Back to all Podcasts The Science Behind AXS-05: How Dextromethorphan and Bupropion Work Together Kristian Dambrino, DNP, PMHNP-BC AUGUST 6, 2025 HMP · The Science Behind AXS-05: How Dextromethorphan and Bupropion Work Together Kristian Dambrino, DNP, PMHNP-BC breaks down the pharmacology of this combination therapy.